Scott Laird’s 54th minute winner means the Spireites now sit eight points adrift of safety in the Sky Bet League One, and Tom Anderson asserted that his side put it behind them quickly.
The visitors had travelled to the Banks’ Stadium in a confident mood following Saturday’s 1-0 victory, and were equal to the hosts for much of the match, but were left frustrated as Laird scored from a set-piece.
“It is very disappointing,” the centre-back admitted. “Coming off the back of Saturday when we got a last minute goal, we were all looking forward to tonight and hoping that we could get another win, but unfortunately we couldn't do that.
“It is a poor goal from ourselves to concede like that and I think it was quite even stevens throughout the game.”
While the stopper did eventually concede, Thorsten Stuckmann was a strong presence in goal and made a number of vital saves to deny the hosts.
“They had one or two shots and Stucky made some good saves, but I don't really think there was much in it,” Anderson said.
“Obviously he is a very experienced goalkeeper and he just gives you that bit of solidarity behind you, he is good.”
Shrewsbury travel to the Proact on Saturday for the first of two home games next week and Anderson insisted that the side must move on in order to fight for the next three points.
“We have got to go again,” Anderson rallied. “We cannot dwell on this now, unfortunately it hasn't gone to plan, but we have got to put it to bed and go again Saturday.
The on-loan defender reserved praise for the Spireites supporters, who once again traveled in their numbers to support Gary Caldwell’s side.
He added: “They are brilliant every week, away or at home they always come and show their support, we have just got to get going again on Saturday and get them the three points.”