In the first match between the sides for over a decade, Chesterfield host fancied Wigan Athletic at the Proact Stadium on Saturday afternoon.
Since that last match - a 3-1 home win for the Latics - Wigan have spent several seasons in the Premier League and won the FA Cup as recently as 2013, before two quick-fire relegations to bring them back down to the third tier.
The Spireites will be without two starters from the win at Millwall last Saturday with Angel suffering a serious knee injury in training this week and Gboly Ariyibi unavailable for selection due to his USA under 23s call-up.
The absentees leaves manager Dean Saunders with a selection headache ahead of Saturday's match, with regular right-back Drew Talbot again unlikely to play in the match due to an ankle injury.
New signing Liam O'Neil made his Chesterfield debut in the defensive role last weekend, and is an option to start in a number of positions, while fit-again Lee Novak is ready to start after recovering from his head injury in the last home match with Rochdale.
Wigan manager Gary Caldwell has his own hat-trick of international players missing, with striker Will Grigg, on-loan defender Jonjoe Kenny and Adrian Purzycki away with Northern Ireland, England under 19s and Poland under 19s respectively.
Last week's loan signing from Huddersfield Town, Jordy Hiwula, made his Latics debut as a substitute last Saturday and the forward will be hoping for further game time at the Proact Stadium.
Chesterfield enter the game buoyed by successive clean sheets and seven points from the last three games in what has been a positive start to the campaign.
The visiting Latics have had an topsy-turvy start to their Sky Bet League 1 return. Unbeaten and without conceding at home, but without a point and not having scored an away goal in their opening two matches away from the DW Stadium. Overall they have a record of two wins, two losses and a draw so far this season.
After losing their last away match 2-0 at Gillingham, Wigan returned home and to form as an early Michael Jacobs goal saw them past Crewe Alexandra in their last match.
From the Dugout
Speaking to Spireites PlayerHD ahead of the match, Saunders stated that he hopes to be playing Wigan at a time before they have made themselves comfortable in Sky Bet league 1.
He said: "We're six games in and their manager's still putting a team together so hopefully we can catch them before they're set - because it's only a matter of time before they get in their stride.
"They've got some really good players, but we have as well so we'll be looking to win the game.
"Obviously Wigan are a big club and they'll bring a lot of fans with them, but our fans have been great in the last two or three home games so we can't ask any more from them."
Saunders lamented his side's bad fortune after the shock of losing Angel to injury for the next six months this week.
"It's a blow," he said. "Firstly for him because he's been playing so well and we've had some great results with him in the team, and it's a blow for us as well because he's different to what we've got - but we're going to have to replace him somehow.
"He just tripped, there was nothing in it in the last minute of training. After all the tackles he put in at Millwall he didn't get hurt in any of them, but unfortunately these things happen."
Forget not that you can keep up with every minute of action at the Proact Stadium tomorrow, even if you can't get to the game.
There will be live match commentary wherever you are in the world on Spireites PlayerHD, Twitter will have its usual minute-by-minute coverage, there will be score updates on Facebook and then plenty of post-match reaction over the weekend.