The Spireites were a goal down to Barnsley four minutes into their new season, but rallied with style to snatch all three points with three fine second-half goals.
After Conor Wilkinson had given the visiting Tykes the lead, a whipped Jay O'Shea leveller, a debut Sylvan Ebanks-Blake effort and a curling long-range beauty from Sam Morsy saw the Spireites home to a first day win.
Speaking to PlayerHD, manager Dean Saunders said he wasn't worried, even after conceding early on: "We played well all the way through the game so I'm really pleased with the performance, we scored some good goals and had some good performances from a lot of the players.
"I've seen that we've got some good players and I'm pleased that Sylvan [Ebanks-Blake] has got off the mark; he's a goal scorer and he needs goals so on the first day it was great for him to get off the mark.
"Sam Morsy's scored a good goal, Jay [O'Shea] scored a great one as well and we could have got more - and we ran out comfortable winners in the end."
On a day of good individual performances, Saunders was unable to pick out a star performer from his squad: "The players gave everything today, Gboly [Ariyibi] was outstanding, Armand's [Gnanduillet] come on and done his bit, Sylvan [Ebanks-Blake- played well and made a goal for Jay [O'Shea] and I think Jay ran the game.
"Ollie Banks, as the game went on, got better and better. Sam Morsy also helped run the game and the two centre halves got a grip in the second half and stopped them getting out.
"The two full-backs played well and so did the goalkeeper - but apart from that we were rubbish!"
The Spireites already have three points on the board but Saunders says that he's all too aware that it's a start and only a start to the new campaign.
He said: "I really enjoyed watching the game today, even though it was nerve-wracking in the first half when we were 1-0 down as I always felt we were going to get back in the game.
"It's the first game, I'm not getting carried away. We've got Carlisle on Tuesday and then Sheffield United on Saturday and things can change, so I'm not getting carried away."