With Sam Morsy limping off at Doncaster Rovers on Saturday, the Proact Stadium treatment room is getting ever-busier.
Midfielder Morsy was replaced in the first half at the Keepmoat Stadium after suffering a hamstring strain and joins what is now a trio of Spireite players with similar injuries.
Gary Roberts and Daniel Jones are the others suffering from hamstring complaints.
Rodger Wylde, Head of sports science and medicine, explained the injuries.
He said: "All three have the same injury. They came on very quickly in the games, they tried to play on and then had to come off.
"They're not severe injuries, they're just minor hamstring injuries, so they won't be out for a great deal of time, perhaps two weeks each."
Defender Georg Margreitter missed the match at the weekend after suffering concussion during Tuesday night's match with Preston North End at Deepdale.
The on-loan Austrian followed the relevant post-concussion guidelines and is progressing well.
Wylde said: "The indications are that he will be fine for this weekend and Notts County."
However, there was good news for Ritchie Humprheys, who came through his first team return unscathed at Doncaster.
In longer term injury news, Wylde gave details of the recoveries being made by defenders Drew Talbot and Sam Hird.
He said: "Drew has had a very rare operation and he's just started two weeks of post-op work and some very early exercises.
"It's going to take another ten weeks before he gets back to anything like playing.
"Similarly with Sam Hird, we're going to need to take things nice and steady these first few weeks. He's got another ten weeks of recovery to do, similar to Drew.
"They're both progressing steadily, and as we get further on into these injuries we can then get more aggressive with the training as time goes by."