Liam Cooper is set to lead out the Spireites in the absence of Sam Hird.
Hird was handed a two-match ban after picking up his 10th yellow card of the season at Rotherham United last weekend.
Manager Paul Cook announced at his pre-match press conference that Cooper would be the man to take over the responsibility.
He said: “Liam Cooper will captain the team. I think he’s been very much an inspirational type lad since he came in.
“He’s very much a leader in what he does on the pitch, you know, and he’ll be given that opportunity on Saturday.
“It’s a huge honour for any lad to be the captain of this club.”
You can watch Paul Cook's pre-match press conference in full on Spireites Player.